Correspondence Address:
Dr. Suresh Vasant Phatak
Department of Radiodiagnosis, Jawaharlal Nehru Medical College, Sawangi (Meghe), Wardha - 442 001, Maharashtra
India

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Respected Sir,

Soft-tissue calcification consists of a broad category of lesions that are commonly encountered routinely by radiologists. If a simple algorithm is used related to the distribution patterns, coupled with full clinical details, such as history and laboratory reports, soft-tissue calcifications can be systematically analyzed. Calcinosis is a condition wherein the deposition of calcium takes place in the region of skin, subcutaneous tissue, muscles, or visceral organs. The distribution pattern of the calcific deposits is seen in two forms: calcinosis universalis or calcinosis circumscripta.[1] In calcinosis circumscripta, calcium is deposited in skin and subcutaneous tissues whereas in calcinosis universalis in which deposition of calcium takes place in skin, subcutaneous tissue, muscles, as well as tendons.[2] Calcium is deposited in the form of calcium phosphate or calcium carbonate. Metabolic and physical factors play a pivotal role in the development of most cases of calcinosis. In cases of hypercalcemia or hyperphosphatemia elevated extracellular levels may result in increased intracellular level and may cause its subsequent crystalline precipitation.[3] Depending on the pathophysiologic mechanisms, calcinosis cutis has been classified into metastatic, dystrophic, idiopathic, or iatrogenic varieties.[4] Soft tissue calcifications may be easily demonstrated on plain radiographs [Figure 1]a and [Figure 1]b but CT scan is more effective in demonstrating the location and extent of calcification.[5]{Figure 1}

To conclude soft-tissue calcifications are common findings seen in daily imaging. By systematic analysis of various parameters like the distribution pattern of the calcified lesions, additional laboratory investigation results, and clinical history, proper differential diagnoses can be approached and a correct diagnosis can be made.

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