Journal of Datta Meghe Institute of Medical Sciences University

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 15  |  Issue : 1  |  Page : 108--113

Autologous platelet-rich fibrin as a sole grafting material in regeneration of large periapical (palatal) defects: Report of four consecutive cases


Prasad Dhadse, Gayatri Ragit, Bhairavi Kale, Shilpa Sridhar 
 Department of Periodontics, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi(M), Wardha, Maharashtra, India

Correspondence Address:
Dr. Prasad Dhadse
Department of Periodontics, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Sawangi (Meghe), Wardha, Maharashtra
India

The maintenance of a tooth with periapical lesion is more often managed by periradicular surgery when the efforts using conventional endodontic (re) treatment prove insufficient to achieve desired outcome. The most critical elements of successful bone regeneration involve the production hermetic seal of the endodontic canal after the root end resection and promotion of early uneventful wound healing using desirable biomaterials, particularly in large-sized intraosseous periapical defects. Yet even after the use of different biomaterials available, the wide varieties of such defects have shown suboptimal outcomes and also took longer healing period. The simple procurement method, ready bioavailability, cost-effectiveness, ease of handling, and remarkable healing potential of platelet-rich fibrin (PRF) in filling the large-sized periapical intrabony defects is presented in this article, with the aim of providing optimal and most elusive environment for wound healing in regenerative procedure. The entire intrabony defects were condensed with autologous PRF as the only grafting material in all four different cases for regeneration. The same surgical technique successfully applied to all four selected cases resulted in an uneventful healing post surgically and almost complete defect fill over 6 months' follow-up. The use of autologous PRF can be recommended for further research in view of its therapeutic use in large-sized intraosseous defects even in different health disciplines; to support the successful outcome identified in this case series.


How to cite this article:
Dhadse P, Ragit G, Kale B, Sridhar S. Autologous platelet-rich fibrin as a sole grafting material in regeneration of large periapical (palatal) defects: Report of four consecutive cases.J Datta Meghe Inst Med Sci Univ 2020;15:108-113


How to cite this URL:
Dhadse P, Ragit G, Kale B, Sridhar S. Autologous platelet-rich fibrin as a sole grafting material in regeneration of large periapical (palatal) defects: Report of four consecutive cases. J Datta Meghe Inst Med Sci Univ [serial online] 2020 [cited 2020 Nov 25 ];15:108-113
Available from: http://www.journaldmims.com/article.asp?issn=0974-3901;year=2020;volume=15;issue=1;spage=108;epage=113;aulast=Dhadse;type=0