|LETTER TO EDITOR
|Year : 2022 | Volume
| Issue : 3 | Page : 808
Expected incidence of thrombocytopenia in influenza patient after ruling out for dengue concurrence
Beuy Joob1, Viroj Wiwanitkit2
1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Biological Science, Joseph Ayo Babalola University, Ikeji-Arakeji, Osun State, Nigeria
|Date of Submission||10-Jun-2019|
|Date of Decision||20-Nov-2019|
|Date of Acceptance||27-Jan-2020|
|Date of Web Publication||2-Nov-2022|
Dr. Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Joob B, Wiwanitkit V. Expected incidence of thrombocytopenia in influenza patient after ruling out for dengue concurrence. J Datta Meghe Inst Med Sci Univ 2022;17:808
|How to cite this URL:|
Joob B, Wiwanitkit V. Expected incidence of thrombocytopenia in influenza patient after ruling out for dengue concurrence. J Datta Meghe Inst Med Sci Univ [serial online] 2022 [cited 2023 Feb 8];17:808. Available from: http://www.journaldmims.com/text.asp?2022/17/3/808/360238
Influenza is an important respiratory tract infection. This viral infection is still the global public health consideration. A nonrespiratory manifestation of influenza is interesting. The hematological findings in influenza include thrombocytopenia. In fact, thrombocytopenia in influenza is reported for relationship with poor clinical course. Nevertheless, there is still no clear explanation for pathophysiology for thrombocytopenia in influenza. In tropical country, there is a chance that influenza can co-occur with other tropical infections. The concurrence between dengue and influenza is possible. In that case, the thrombocytopenia due to dengue might be seen in the patient with co-infection.
Here, the authors use the mathematical model to estimate an expected incidence of thrombocytopenia in an influenza patient that is already ruled out for dengue concurrence. The model is developed based on the previous reports on the incidence of thrombocytopenia in influenza, and the incidence of concurrence between influenza and dengue. The data from Thailand, a tropical country in Indochina, are primarily used for modeling. Based on the available data, the observed incidence of thrombocytopenia in influenza is equal to 10.4% and 53.0%, and the observed incidence of concurrence between influenza and dengue is equal to 1.08% (3 from 278 influenza patients). Based on these data, the expected incidence for thrombocytopenia in influenza patient that is already ruled out for dengue concurrence is between 9.32% and 51.92%. The expected rate is considerable high.
Further study on the exact pathophysiology of influenza-induced thrombocytopenia is required.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
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