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ORIGINAL ARTICLE
Year : 2022  |  Volume : 17  |  Issue : 1  |  Page : 25-29

Study of gram-positive isolates from cases of septicemia and their antibiotic sensitivity pattern with special reference to methicillin-resistant Staphylococcus aureus


Department of Microbiology, JNMC, Wardha, Maharashtra, India

Correspondence Address:
Dr. Shital Moreshwarrao Mahajan
Department of Microbiology, JNMC, Sawangi, Wardha, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdmimsu.jdmimsu_210_22

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Background: Infections of the bloodstream are a leading source of illness and mortality in all types of communities. Bacteremia is the presence of bacteria in the bloodstream for long or short periods. Aim and Objectives: Dissemination of the bacteria throughout the body with evidence of systemic responses toward microorganisms is septicemia. Many organisms including Gram positive such as Coagulase negative staphylococci, Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae, and Enterococcus faecium can cause septicemia. Many precipitating factors such as presence of intravenous catheters, immunocompromised state, and use of cytotoxic drugs may lead to increase in cases of septicemia. Isolation of the offending pathogens and knowledge about sensitivity and resistance pattern of the isolates remain the mainstay of the diagnosis. This study was conducted to cite the bacteriological etiology of septicemia in adults as well as in neonates and to decide the strategy for the cure of septicemia cases along with their antibiotic susceptibility profile. Materials and Methods: Duration of this study was 3 months. In this duration, 100 blood samples from suspected cases of septicemia were processed. Results: Gram positive organisms isolated from the specimens were collected and identified by standard protocols. Antibiotic sensitivity and detection of methicillin resistant Staphylococcus aureus were done by using Kirby Bauer disc diffusion method. Conclusion: Various causative agents were isolated from blood samples. Some of them are resistant to the drugs that are commonly used for the treatment of septicemia. Hence, isolation of the etiological agent along with the detection of its antibiogram pattern is important for early diagnosis and treatment of cases of septicemia.


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