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ORIGINAL ARTICLE
Year : 2021  |  Volume : 16  |  Issue : 1  |  Page : 158-165

Evaluation of erosive and cariogenic potential of pediatric liquid formulated drugs commonly prescribed in India: A physiochemical study


Department of Pediatric and Preventive Dentistry, K.M. Shah Dental College and Hospital, Sumandeep Vidhyapeeth, Vadodara, Gujarat, India

Correspondence Address:
Dr. Anshula Neeraj Deshpande
Department of Pediatric and Preventive Dentistry, K.M. Shah Dental College and Hospital, Sumandeep Vidhyapeeth, Vadodara, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1319-4534.322619

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Context: Many children receive medications for recurrent acute illness and vitamin supplements prescribed by a pediatrician. These medications for young children are in form of syrup and emulsion which are of high sugar content and low pH. These medications make teeth susceptible tooth erosion. Aim: The aim was to evaluate the erosive and cariogenic potential of mid cariogenic potential of pediatric drugs prescribed in India by physicochemical methods. Materials and Methods: The drugs used in this study compromised 96 liquid drug preparations commercially available as oral solution, suspension, elixir, syrup, and drops commonly prescribed for various ailments for children. Tests were performed in triplicate by a calibrated researcher. The endogenous pH of each sample was determined using digital pH meter HI-253. The measurements of the total soluble solids contents were done using the method proposed by the Ayurvedic Formulary of India and the sugar content was determined according to the prescription. Descriptive statistics were employed to compare the results. Results: All drug classes showed acidic pH, and the lowest mean was found for anticonvulsants (4.2 ± 0.20). The variation in the total titratable acidity was from 0.0% to 0.03% among all the drug classes. The highest TSS values were found in bronchodilators 52.75 ± 14.32. Almost all the syrups failed to mention syrup base in their content. Conclusion: It was found that sugar is present in almost all the commercially available pediatric syrups, and a lot of the syrups have their pH close to the critical pH of teeth.


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