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ORIGINAL ARTICLE
Year : 2021  |  Volume : 16  |  Issue : 1  |  Page : 108-114

A study of neurocognitive dysfunction in HIV-positive patients in a tertiary care center in South India


1 Department of General Medicine, JSSAHER, Mysuru, Karnataka, India
2 Department of Undergraduate Student JSSMC, JSSAHER, Mysuru, Karnataka, India

Correspondence Address:
Dr. Rajendra Prasad Shivaswamy
JSSMC, JSSAHER, Mysore, Karnataka
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1319-4534.322599

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Context: HIV-associated neurocognitive disorder (HAND) is an ongoing problem among HIV-positive patients, irrespective of whether the patients are on antiretroviral treatment (ART) or not. ART has helped in halting the progression of the disease, but still, research needs to be done in reversing the disorder. Patients on ART are still known to have a mild neurocognitive disorder. The prevalence of HAND is estimated in approximately 40%–50% of all cases. Aims: (1) To determine the presence of neurocognitive dysfunction in HIV-positive patients. (2) To determine sociodemographic factors that influence this condition. (3) To determine the relationship between CD4 count and neurocognitive dysfunction. Settings and Design: The sampling technique was purposive sampling. A cross-sectional study was undertaken in a sample size of 162 among patients attending the outpatient department of medicine department using the International HIV Dementia Scale (IHDS). Subjects and Methods: IHDS has the maximum possible score of 12 points. A patient with a score of ≤10 should be evaluated further for possible dementia. Statistical Analysis: Data entry was done in an Excel sheet. Data analysis was done using SPSS. Results: It was found that of the 162 patients who participated in the study, 71% were found to be at risk for the neurocognitive disorder. The factors which had a significant association were age, education, spouse alive or not, and HIV status of the spouse. Conclusion: It was found that out that neurocognitive disorder is common in the ART era and also it can be detected by simple bedside tests.


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