|
 
 |
| LETTER TO EDITOR |
|
| Year : 2020 | Volume
: 15
| Issue : 2 | Page : 336 |
|
Blood cell disorder in coronavirus disease 2019 infection
Won Sriwijitalai1, Viroj Wiwanitkit2
1 TWS Medical Academic Center, Bangkok, Thailand
2 Dr. D. Y. Patil University, Pune, Maharashtra, India; Hainan Medical University, Haikou, China
| Date of Submission | 28-Feb-2020 |
| Date of Decision | 05-Mar-2020 |
| Date of Acceptance | 10-Mar-2020 |
| Date of Web Publication | 21-Dec-2020 |
Correspondence Address:
Dr. Won Sriwijitalai
TWS Medical Academic Center, Bangkok
Thailand
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jdmimsu.jdmimsu_53_20
How to cite this article:
Sriwijitalai W, Wiwanitkit V. Blood cell disorder in coronavirus disease 2019 infection. J Datta Meghe Inst Med Sci Univ 2020;15:336 |
Sir,
Coronavirus disease 2019 (COVID-19) infection is a new viral disease that causes respiratory illness originating from China.[1] This respiratory infection becomes a new global public health threat in 2020. It exists in more than 30 countries around the world. The disease can spread from human to human and cause a wide outbreak in many areas. In addition to respiratory manifestation, there are also nonrespiratory manifestations of this new disease. An important clinical manifestation is a hematological manifestation. Blood cell disorder is observable.
In published reports from China, anemia is observable.[2],[3] The exact pathogenesis of anemia is not known. It is also questionable whether the anemia is a background illness of the patient or it is induced by the virus infection. In addition, an increased erythrocyte sedimentation rate is also another important laboratory manifestation.[2],[3] Focusing on white blood cells, a complete blood count can show a specific pattern of leukocytopenia with lymphocytopenia.[2],[3],[4],[5] Considering data on 314 cases from recent referencing publications,[2],[3],[4] lymphocytopenia is detected in 216 cases (68.79%). For platelets, thrombocytopenia is a possible finding from complete blood count. This problem might lead to the missed diagnosis of other common viral infections such as dengue.[6] A practitioner has to recognize the possible pattern of abnormal blood cells in basic primary hematological investigation on patients with suspicious COVID-19.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Hsia W. Emerging new coronavirus infection in Wuhan, China: Situation in early 2020. Case Study Case Rep 2020;10:8-9.  |
| 2. | Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497-506. |
| 3. | Liu K, Fang YY, Deng Y, Liu W, Wang MF, Ma JP, et al. Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl) 2020;133:1025-31. [doi: 10.1097/CM9.0000000000000744]. |
| 4. | Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323:1061-9. doi:10.1001/jama.2020.1585. |
| 5. | Chen L, Liu HG, Liu W, Liu J, Liu K, Shang J, et al. Analysis of clinical features of 29 patients with 2019 novel coronavirus pneumonia. Zhonghua Jie He He Hu Xi Za Zhi 2020;43:E005. |
| 6. | Joob B, Wiwanitkit V. COVID-19 in medical personnel: Observation from Thailand. J Hosp Infect 2020;104:453. doi: 10.1016/j.jhin.2020.02.016. Epub 2020 Feb 27. |
|
Search Pubmed for