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 Table of Contents  
Year : 2020  |  Volume : 15  |  Issue : 2  |  Page : 336

Blood cell disorder in coronavirus disease 2019 infection

1 TWS Medical Academic Center, Bangkok, Thailand
2 Dr. D. Y. Patil University, Pune, Maharashtra, India; Hainan Medical University, Haikou, China

Date of Submission28-Feb-2020
Date of Decision05-Mar-2020
Date of Acceptance10-Mar-2020
Date of Web Publication21-Dec-2020

Correspondence Address:
Dr. Won Sriwijitalai
TWS Medical Academic Center, Bangkok
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jdmimsu.jdmimsu_53_20

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How to cite this article:
Sriwijitalai W, Wiwanitkit V. Blood cell disorder in coronavirus disease 2019 infection. J Datta Meghe Inst Med Sci Univ 2020;15:336

How to cite this URL:
Sriwijitalai W, Wiwanitkit V. Blood cell disorder in coronavirus disease 2019 infection. J Datta Meghe Inst Med Sci Univ [serial online] 2020 [cited 2021 Jan 20];15:336. Available from: http://www.journaldmims.com/text.asp?2020/15/2/336/304265


Coronavirus disease 2019 (COVID-19) infection is a new viral disease that causes respiratory illness originating from China.[1] This respiratory infection becomes a new global public health threat in 2020. It exists in more than 30 countries around the world. The disease can spread from human to human and cause a wide outbreak in many areas. In addition to respiratory manifestation, there are also nonrespiratory manifestations of this new disease. An important clinical manifestation is a hematological manifestation. Blood cell disorder is observable.

In published reports from China, anemia is observable.[2],[3] The exact pathogenesis of anemia is not known. It is also questionable whether the anemia is a background illness of the patient or it is induced by the virus infection. In addition, an increased erythrocyte sedimentation rate is also another important laboratory manifestation.[2],[3] Focusing on white blood cells, a complete blood count can show a specific pattern of leukocytopenia with lymphocytopenia.[2],[3],[4],[5] Considering data on 314 cases from recent referencing publications,[2],[3],[4] lymphocytopenia is detected in 216 cases (68.79%). For platelets, thrombocytopenia is a possible finding from complete blood count. This problem might lead to the missed diagnosis of other common viral infections such as dengue.[6] A practitioner has to recognize the possible pattern of abnormal blood cells in basic primary hematological investigation on patients with suspicious COVID-19.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Hsia W. Emerging new coronavirus infection in Wuhan, China: Situation in early 2020. Case Study Case Rep 2020;10:8-9.  Back to cited text no. 1
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497-506.  Back to cited text no. 2
Liu K, Fang YY, Deng Y, Liu W, Wang MF, Ma JP, et al. Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl) 2020;133:1025-31. [doi: 10.1097/CM9.0000000000000744].  Back to cited text no. 3
Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323:1061-9. doi:10.1001/jama.2020.1585.  Back to cited text no. 4
Chen L, Liu HG, Liu W, Liu J, Liu K, Shang J, et al. Analysis of clinical features of 29 patients with 2019 novel coronavirus pneumonia. Zhonghua Jie He He Hu Xi Za Zhi 2020;43:E005.  Back to cited text no. 5
Joob B, Wiwanitkit V. COVID-19 in medical personnel: Observation from Thailand. J Hosp Infect 2020;104:453. doi: 10.1016/j.jhin.2020.02.016. Epub 2020 Feb 27.  Back to cited text no. 6


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