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ORIGINAL ARTICLE
Year : 2019  |  Volume : 14  |  Issue : 3  |  Page : 196-201

The Effect of intrathecal magnesium sulfate to bupivacaine-fentanyl subarchanoid block for infraumblical surgeries


Department of Anesthesiology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India

Correspondence Address:
Dr. Jayashree Sen
Department of Anesthesiology, Jawaharlal Nehru Medical College, Sawangi (M), Wardha, Maharashtra
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdmimsu.jdmimsu_83_19

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Background: Subarachnoid block is a safe and inexpensive technique , most versatile regional block for infraumbilical surgeries. Adjuvants such as Fentanyl is the most commonly used. It has been shown that the duration of postoperative analgesia also can be prolonged when magnesium is given as an adjunct for peripheral nerve blocks. Aim and Objectives: the present study was designed to examine whether addition of intrathecal magnesium sulfate would enhance the analgesic efficacy of intrathecal bupivacaine and fentanyl in patients undergoing infra umbilical surgeries. And with the primary objective to study the efficacy, onset and duration of analgesia , hemodynamic variability during block and duration of motor block and secondary objective to know adverse effect of the drugs. Setting and Design Prospective, randomised controlled observational study. Material and Methods: 70 patients were selected , they were randomly allocated into two groups of 35 each using computer generated data. Group S: Intrathecal administration of 2.5 mL (12.5 mg) of hyperbaric bupivacaine + 0.5 mL (25 mcg) of fentanyl + 1 mL of normal saline. Group M: Intrathecal administration of 2.5 mL (12.5 mg) of hyperbaric bupivacaine + 0.5 mL (25 mcg) of fentanyl +1.0 ml (50 mg) of magnesium sulphate. Statistical Analysis- done by using descriptive and inferential statistics using chisquare test and student's unpaired t test and software used in the analysis were SPSS 22.0 version and Graph Pad Prism 6.0 version and p<0.05 is considered as level of significance. Results: We conclude that when magnesium is added in the mixture of bupivacaine and fentanyl through spinal route it significantly prolonged postoperative analgesia without any significant haemodynamic variations and adverse effects. Conclusion: Adding magnesium in the mixture of bupivacaine and fentanyl through spinal route for effective postoperative analgesia is without significant haemodynamic variations and adverse effects.


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