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ORIGINAL ARTICLE
Year : 2018  |  Volume : 13  |  Issue : 1  |  Page : 30-33

Retrospective analysis of incidence of central nervous system tumors in a tertiary care centre: A 3-year study


Department of Pathology, Postgraduate Institute of Medical Sciences, Rohtak, Haryana, India

Correspondence Address:
Dr. Sant Prakash Kataria
Department of Pathology, Postgraduate Institute of Medical Sciences, Rohtak, Haryana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jdmimsu.jdmimsu_45_18

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Introduction: Tumors of the central nervous system (CNS) are rare neoplasm constituting <2% of all malignancies. In India, CNS tumors constitute about 1.9% of all tumors. The objective of this study is to have an insight into the pattern of CNS lesions over a period of 3 years in a tertiary care hospital retrospectively. Materials and Methods: A retrospective study was conducted at the Department of Pathology, Pandit Bhagwat Dayal Sharma, Postgraduate Institute of Medical Sciences (PGIMS), Rohtak, a tertiary care hospital, over a period of 3 years. Two hundred and thirty-nine cases of CNS lesions reported during this period comprised the patients of the study. All data and information were archived from the case records maintained in the histopathological division of the Department of Pathology. Results: The age of the patients ranged from 2 to 65 years, with the mean age of 43.28 years. Majority of the cases were seen in the age group of 28–58 years (70%). Overall, males slightly outnumbered females; however, meningioma is an exception with higher rates in females. Majority of tumors were intracranial (96.2%) and remaining (3.76%) were spinal. Of the intracranial cases, frontal lobe was the most common site (25.5%) followed by temporoparietal lobe (13.2%). Astrocytomas comprising 84 (35.2%) cases constituted the largest group of the present study, followed by meningioma constituting 22.2% of all CNS tumors and glioblastoma forming the largest subtype of astrocytic tumor (35.7%). Among 16 pediatric cases, astrocytomas (6 cases) were more common as compared to medulloblastoma (4 cases). Conclusion: The most frequent type of CNS tumor in the present study was astrocytoma, followed by meningioma. The ratio of male: female for all CNS tumors was 1.06:1. Females outnumbered males in meningioma (2.8:1).


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